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Article

High prevalence of clonal hematopoiesis-type genomic abnormalities in cell-free DNA in invasive gliomas after treatment.

International journal of cancer - 1 Jun 2021

Okamura Ryosuke, Piccioni David E, Boichard Amélie, Lee Suzanna, Jimenez Rebecca E, Sicklick Jason K, Kato Shumei, Kurzrock Razelle

Abstract excerpt

Plasma cell-free DNA (cfDNA) is emerging as an important diagnostic tool in cancer. However, cfDNA alterations may differ from those in tissue and sometimes may reflect processes unrelated to the cancer, including clonal hematopoiesis (CH). We examined plasma cfDNA, tested by next-generation sequencing (NGS), for characterized alterations (excluding variants of unknown significance) in 135 patients with invasive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33497479
DOI: 10.1002/ijc.33481
PMCID: PMC8048515

Genes

ATM
GNAS
JAK2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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