Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study.

doi:10.1158/1078-0432.CCR-19-2533

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Article

Clinical Utility of Plasma Cell-Free DNA in Adult Patients with Newly Diagnosed Glioblastoma: A Pilot Prospective Study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2020

Bagley Stephen J, Nabavizadeh S Ali, Mays Jazmine J, Till Jacob E, Ware Jeffrey B, Levy Scott, Sarchiapone Whitney, Hussain Jasmin, Prior Timothy, Guiry Samantha, Christensen Theresa, Yee Stephanie S, Nasrallah MacLean P, Morrissette Jennifer J D, Binder Zev A, O'Rourke Donald M, Cucchiara Andrew J, Brem Steven, Desai Arati S, Carpenter Erica L

Abstract excerpt

PURPOSE: The clinical utility of plasma cell-free DNA (cfDNA) has not been assessed prospectively in patients with glioblastoma (GBM). We aimed to determine the prognostic impact of plasma cfDNA in GBM, as well as its role as a surrogate of tumor burden and substrate for next-generation sequencing (NGS). EXPERIMENTAL DESIGN: We conducted a prospective cohort study of 42 patients with newly diagnosed GBM. Plasma...

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Identifiers

PMID: 31666247
DOI: 10.1158/1078-0432.CCR-19-2533
PMCID: PMC6980766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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