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Article

Cell-free DNA - Minimally invasive marker of hematological malignancies.

European journal of haematology - 1 Oct 2017

Kubaczkova Veronika, Vrabel David, Sedlarikova Lenka, Besse Lenka, Sevcikova Sabina

Abstract excerpt

Although tumor cells are the most reliable source of tumor DNA, biopsy of the tumor is an invasive procedure that should be avoided in some cases. The main limitation of any biopsy is sampling of one tumor site, which may not represent all malignant clones due to the heterogeneity of the tumor. These clones respond to treatment differently and thus directly influence survival of the patient. Circulating cell-free...

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PMID: 28692178
DOI: 10.1111/ejh.12925

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