Article
Dynamics of cell-free DNA in predicting response in adult diffuse glioma on chemoradiotherapy.
Cancer genetics - 1 Nov 2022
Husain Adil, Mishra Sridhar, Hadi Rahat, Sahu Avnish, Kumari Swati, Rastogi Madhup, Khurana Rohini, Shukla Saumya, Siddiqui Mohammed Haris, Husain Nuzhat
Abstract excerpt
BACKGROUND: Adult diffuse glioma (ADG) is a heterogeneous primary brain tumor with a variable prognosis and treatment response. Tissue biomarkers and molecular genetic profiling form an integral part of diagnosis and prognostication. However, obtaining tissue in inoperable locations and diagnosis of recurrence can be an issue. Cell-free DNA (cfDNA) may help to meet these challenges in the management of ADG....
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