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Article

Microtubule pivoting enables mitotic spindle assembly in S. cerevisiae.

The Journal of cell biology - 1 Mar 2021

Fong Kimberly K, Davis Trisha N, Asbury Charles L

Abstract excerpt

To assemble a bipolar spindle, microtubules emanating from two poles must bundle into an antiparallel midzone, where plus end-directed motors generate outward pushing forces to drive pole separation. Midzone cross-linkers and motors display only modest preferences for antiparallel filaments, and duplicated poles are initially tethered together, an arrangement that instead favors parallel interactions. Pivoting of...

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Source

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Identifiers

PMID: 33464308
DOI: 10.1083/jcb.202007193
PMCID: PMC7814349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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