Article
Stu1p is physically associated with beta-tubulin and is required for structural integrity of the mitotic spindle.
Molecular biology of the cell - 1 Jun 2002
Yin Hongwei, You Liru, Pasqualone Danielle, Kopski Kristen M, Huffaker Tim C
Abstract excerpt
Formation of the bipolar mitotic spindle relies on a balance of forces acting on the spindle poles. The primary outward force is generated by the kinesin-related proteins of the BimC family that cross-link antiparallel interpolar microtubules and slide them past each other. Here, we provide evidence that Stu1p is also required for the production of this outward force in the yeast Saccharomyces cerevisiae. In the...
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