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Article

Augmenting E Protein Activity Impairs cDC2 Differentiation at the Pre-cDC Stage.

Frontiers in immunology - 1 Jan 2020

Bajana Sandra, Thomas Kevin, Georgescu Constantin, Zhao Ying, Wren Jonathan D, Kovats Susan, Sun Xiao-Hong

Abstract excerpt

Dendritic cell (DC) specification and differentiation are controlled by a circuit of transcription factors, which regulate the expression of DC effector genes as well as the transcription factors themselves. E proteins are a widely expressed basic helix-loop-helix family of transcription factors whose activity is suppressed by their inhibitors, ID proteins. Loss-of-function studies have demonstrated the essential...

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Identifiers

PMID: 33391258
DOI: 10.3389/fimmu.2020.577718
PMCID: PMC7775562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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