Genetic susceptibilities and prediction modeling of carbamazepine and allopurinol-induced severe cutaneous adverse reactions in Vietnamese.

doi:10.2217/pgs-2019-0146

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Article

Genetic susceptibilities and prediction modeling of carbamazepine and allopurinol-induced severe cutaneous adverse reactions in Vietnamese.

Pharmacogenomics - 1 Jan 2021

van Nguyen Dinh, Chu Hieu Chi, Vidal Christopher, Fulton Richard B, Nguyen Nguyet Nhu, Quynh Do Nga Thi, Tran Tu Linh, Nguyen Thuy Ninh, Thu Nguyen Ha Thi, Chu Hanh Hong, Thanh Thuc Huyen Thi, Minh Le Huong Thi, van Nunen Sheryl, Anderson Janet, Fernando Suran L

Abstract excerpt

Aims: To determine genetic susceptibility markers for carbamazepine (CBZ) and allopurinol-induced severe cutaneous adverse reactions (SCARs) in Vietnamese. Methods: A case-control study was performed involving 122 patients with CBZ or allopurinol-induced SCARs and 120 drug tolerant controls. Results:HLA-B*58:01 was strongly associated with allopurinol-induced SCARs and strongly correlated with SNP rs9263726....

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PMID: 33356553
DOI: 10.2217/pgs-2019-0146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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