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Article

Associations of HLA genetic variants with carbamazepine-induced cutaneous adverse drug reactions: An updated meta-analysis.

Clinical and translational science - 1 Aug 2022

Biswas Mohitosh, Ershadian Maliheh, Shobana John, Nguyen Ai-Hoc, Sukasem Chonlaphat

Abstract excerpt

Aggregated risk of carbamazepine (CBZ)-induced cutaneous adverse drug reactions (cADRs) with different HLA variants are unclear and limited in terms of the power of studies. This study aimed to assess the aggregated risk of CBZ-induced cADRs associated with carrying the following HLA variants: HLA-B*15:02, HLA-B*15:11, HLA-B*15:21, HLA-B*38:02, HLA-B*40:01, HLA-B*46:01, HLA-B*58:01, HLA-A*24:02, and HLA-A*31:01....

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Anticonvulsants
Benzodiazepines
Carbamazepine
Drug-Induced Adverse Reactions
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35599240
DOI: 10.1111/cts.13291
PMCID: PMC9372413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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