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Article

Developing pharmacogenetic screening methods for an emergent country: Vietnam

1 Jan 2019

Abstract excerpt

BACKGROUND: The finding of strong associations between certain human leukocyte antigen (HLA) genotypes and the development of severe cutaneous adverse drug reactions (SCARs), [for example, HLA-B*57:01 and abacavir (ABC), HLA-B*15:02 and carbamazepine (CBZ) and HLA-B*58:01 and allopurinol], has led to HLA screening being used to prevent SCARs. Screening has been shown to be of great benefit in a number of studies....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31198488
DOI: 10.1016/j.waojou.2019.100037

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