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Positive and negative associations of HLA class I alleles with allopurinol-induced SCARs in Koreans

8 Feb 2011

Abstract excerpt

Recent investigations suggest genetic susceptibility of allopurinol-induced severe cutaneous adverse reactions (SCARs). However, the strength of association was variable according to phenotypes and ethnic backgrounds. To explore genetic markers for allopurinol-induced SCARs in Koreans, we genotyped human leukocyte antigen (HLA) class I alleles of 25 cases of allopurinol-induced SCARs (20 cases of drug-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21301380
DOI: 10.1097/fpc.0b013e32834282b8

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