Article
Risk factors of allopurinol-induced severe cutaneous adverse reactions in a Thai population.
Pharmacogenetics and genomics - 1 Jul 2017
Saksit Niwat, Tassaneeyakul Wichittra, Nakkam Nontaya, Konyoung Parinya, Khunarkornsiri Usanee, Chumworathayi Pansu, Sukasem Chonlaphat, Suttisai Sumitra, Piriyachananusorn Napacha, Tiwong Pawinee, Chaiyakunapruk Nathorn, Sawanyawisuth Kittisak, Rerkpattanapipat Ticha, Tassaneeyakul Wongwiwat
Abstract excerpt
BACKGROUND: Allopurinol is one of the most common causes of severe cutaneous adverse drug reactions (SCARs) including drug reactions with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). This study identified the risk factors associated with the development of allopurinol-induced SCARs in a Thai population. PATIENTS AND METHODS: Eighty-six...
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