Article
Pharmacogenomics of drug-induced hypersensitivity reactions: challenges, opportunities and clinical implementation.
Asian Pacific journal of allergy and immunology - 1 Jun 2014
Sukasem Chonlaphat, Puangpetch Apichaya, Medhasi Sadeep, Tassaneeyakul Wichittra
Abstract excerpt
Drug hypersensitivity reactions affect many patients leading to a variety of clinical manifestations, mainly the cutaneous adverse reactions ranging from milder skin reactions to severe cutaneous adverse reactions (SCARs). Hypersensitivity reactions are unpredictable and are thought to have an underlying genetic etiology, as suggested by case reports. With the scientific knowledge of pharmacogenomics and the...
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