Article

HLA-B*58:01 is an Incomplete Predictor of Allopurinol-Induced Severe Cutaneous Adverse Reactions

2025-05-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Importance</h4> Carriage of HLA-B*58:01 has been shown to have a strong association with the development of allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) and drug reaction and eosinophilia and systemic symptoms (DRESS) in many populations globally; however, there is a critical need to determine if this is generalizable to varying populations including t...

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Literature Corpus work: bf5f01b1-917b-52d9-9780-ee9c4b09bdd3
DOI: 10.1101/2025.05.23.25328236

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