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Article

Immunopathogenesis and risk factors for allopurinol severe cutaneous adverse reactions.

Current opinion in allergy and clinical immunology - 1 Aug 2016

Wang Chuang-Wei, Dao Ro-Lan, Chung Wen-Hung

Abstract excerpt

PURPOSE OF REVIEW: The article reviews the immunopathogenesis and risk factors related to allopurinol-induced severe cutaneous adverse reactions (SCARs). RECENT FINDINGS: For years, allopurinol remains one of the leading cause for SCARs worldwide. The pathogenesis of allopurinol-induced SCARs have been discovered in recent years. HLA-B58 : 01 has been found to be strongly associated with allopurinol-SCARs with...

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Identifiers

PMID: 27362322
DOI: 10.1097/ACI.0000000000000286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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