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Article

Genetic markers associated with cutaneous adverse drug reactions to allopurinol: a systematic review.

Pharmacogenomics - 1 Jan 2015

Jarjour Samantha, Barrette Mathieu, Normand Valérie, Rouleau Jean Lucien, Dubé Marie-Pierre, de Denus Simon

Abstract excerpt

Pharmacogenomic markers in the HLA coding genes have been associated with drug hypersensitivity of multiple drugs, including allopurinol. In this systematic review, we summarize the pharmacogenomic evidence available regarding allopurinol-induced cutaneous adverse drug reactions (cADRs). We found that the HLA-B*5801 allele was significantly associated with the risk of severe cADRs in the Han Chinese, Korean,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25965122
DOI: 10.2217/pgs.15.21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic markers associated with cutaneous adverse drug reactions to allopurinol: a systematic review.PMID 25965122Read ↗

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