Article
Epidemiology and Molecular-Pathologic Characteristics of CpG Island Methylator Phenotype (CIMP) in Colorectal Cancer.
Clinical colorectal cancer - 1 Jun 2021
Advani Shailesh M, Swartz Michael D, Loree Jonathan, Davis Jennifer S, Sarsashek Amir Mehvarz, Lam Michael, Lee Michael Sangmin, Bressler Jan, Lopez David S, Daniel Carrie R, Morris Van, Shureqi Imad, Kee Bryan, Dasari Arvind, Vilar Eduardo, Overman Michael, Hamilton Stanley, Maru Dipen, Braithwaite Dejana, Kopetz Scott
Abstract excerpt
BACKGROUND: CpG island methylator phenotype (CIMP) forms a distinct epigenetic phenotype in colorectal cancer (CRC). Though associated with distinct clinicopathologic characteristics, limited evidence exists of the association of CIMP with patient's reported lifestyle factors and tumor molecular characteristics. We assessed the associations of these characteristics in a pooled analysis of CRC patients. PATIENTS...
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