Article
CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
Archives of pathology & laboratory medicine - 1 Oct 2008
Lee Sun, Cho Nam-Yun, Yoo Eun Joo, Kim Jung Ho, Kang Gyeong Hoon
Abstract excerpt
CONTEXT: CpG island methylator phenotype (CIMP) designates a subset of colorectal cancers featuring concordant hypermethylation of multiple promoter CpG islands. Little is known about the clinical outcome or histologic characteristics of CIMP-positive colorectal cancers defined by recently identified CpG island methylator phenotype panels. OBJECTIVE: To investigate and compare the molecular and clinicopathologic...
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