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Article

Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases.

Cancer research - 15 Oct 2008

Barault Ludovic, Charon-Barra Céline, Jooste Valérie, de la Vega Mathilde Funes, Martin Laurent, Roignot Patrick, Rat Patrick, Bouvier Anne-Marie, Laurent-Puig Pierre, Faivre Jean, Chapusot Caroline, Piard Francoise

Abstract excerpt

The CpG island methylator phenotype (CIMP) is a distinct phenotype in colorectal cancer, associated with specific clinical, pathologic, and molecular features. However, most of the studies stratified methylation according to two subgroups (CIMP-High versus No-CIMP/CIMP-Low). In our study, we defined three different subgroups of methylation (No-CIMP, CIMP-Low, and CIMP-High) and evaluated the prognostic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18922929
DOI: 10.1158/0008-5472.CAN-08-1171

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases.PMID 18922929Read ↗

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