Article
Meta-Analysis of the Prognostic and Predictive Role of the CpG Island Methylator Phenotype in Colorectal Cancer.
Disease markers - 1 Jan 2022
Wang Jing, Deng Zhujun, Lang Xiaoqiang, Jiang Juan, Xie Kang, Lu Sifen, Hu Qiongxia, Huo Yuwei, Xiong Xinru, Zhu Niu, Zhang Wengeng
Abstract excerpt
Background: Various studies have produced contradictory results on the prognostic role of the CpG island methylator phenotype (CIMP) among colorectal cancer (CRC) patients. Although a meta-analysis published in 2014 reported a worse prognosis of CIMP among CIMP-high (CIMP-H) CRC patients, the sample sizes of the major included studies were small. In this study, we included the most recent studies with large...
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