Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single Nucleotide Polymorphism rs11136000 of CLU Gene (Clusterin, ApoJ) and the Risk of Late-Onset Alzheimer's Disease in a Central European Population.

Neurochemical research - 1 Feb 2021

Balcar Vladimir J, Zeman Tomáš, Janout Vladimír, Janoutová Jana, Lochman Jan, Šerý Omar

Abstract excerpt

Clusterin (CLU; also known as apolipoprotein J, ApoJ) is a protein of inconstant structure known to be involved in diverse processes inside and outside of brain cells. CLU can act as a protein chaperon or protein solubilizer, lipid transporter as well as redox sensor and be anti- or proapoptotic, depending on context. Primary structure of CLU is encoded by CLU gene which contains single nucleotide polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Clusterin

Share to Cognitive Dysfunction

Share to Czech Republic

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 33206315
DOI: 10.1007/s11064-020-03176-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single Nucleotide Polymorphism rs11136000 of CLU Gene (Clusterin, ApoJ) and the Risk of Late-Onset Alzheimer's Disease in a Central European Population.PMID 33206315Read ↗

Association of clusterin gene polymorphisms with late-onset Alzheimer's disease.Semantic proximity Read ↗

The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort.Semantic proximity Read ↗

Implication of CLU gene polymorphisms in Chinese patients with Alzheimer's disease.Semantic proximity Read ↗

Genetic variation in clusterin gene and Alzheimer's disease risk in Han Chinese.Semantic proximity Read ↗

Genetic association between clusterin polymorphisms and Alzheimer's disease in a Japanese population.Semantic proximity Read ↗

Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer's disease cohorts.Semantic proximity Read ↗

Association between CLU gene rs11136000 polymorphism and Alzheimer's disease: an updated meta-analysis.Semantic proximity Read ↗

Implication of common and disease specific variants in CLU, CR1, and PICALM.Semantic proximity Read ↗

Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: cohort studies and meta-analyses of 362,338 individuals.Semantic proximity Read ↗

[Analysis of clusterin gene (CLU/APOJ) polymorphism in Alzheimer's disease patients and in normal cohorts from Russian populations].Semantic proximity Read ↗

Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk.Semantic proximity Read ↗

Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other PathologiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.