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Implication of common and disease specific variants in CLU, CR1, and PICALM.

Neurobiology of aging - 1 Aug 2012

Ferrari Raffaele, Moreno Jorge H, Minhajuddin Abu T, O'Bryant Sid E, Reisch Joan S, Barber Robert C, Momeni Parastoo

Abstract excerpt

Two recent genome-wide association studies (GWAS) for late onset Alzheimer's disease (LOAD) revealed 3 new genes: clusterin (CLU), phosphatidylinositol binding clathrin assembly protein (PICALM), and complement receptor 1 (CR1). In order to evaluate association with these genome-wide association study-identified genes and to isolate the variants contributing to the pathogenesis of LOAD, we genotyped the top...

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Risk Factors
Alzheimer Disease
Clusterin
Genetic Markers
Monomeric Clathrin Assembly Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Complement 3b

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Identifiers

PMID: 22402018
DOI: 10.1016/j.neurobiolaging.2012.01.110

Genes

PICALM
CLU

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Implication of common and disease specific variants in CLU, CR1, and PICALM.PMID 22402018Read ↗

The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels.Semantic proximity Read ↗

The three new pathways leading to Alzheimer's disease.Semantic proximity Read ↗

Lack of association of CR1, PICALM and CLU gene polymorphisms with Alzheimer disease in a Polish population.Semantic proximity Read ↗

Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old.Semantic proximity Read ↗

Replication of CLU, CR1, and PICALM associations with alzheimer disease.Semantic proximity Read ↗

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).Semantic proximity Read ↗

New genetic players in late-onset Alzheimer's diseaseSemantic proximity Read ↗

Implication of a genetic variant at PICALM in Alzheimer’s disease patients and centenarians.Semantic proximity Read ↗

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Effect of CLU and PICALM polymorphisms on AD risk: A study from south India.Semantic proximity Read ↗

Late-Onset Alzheimer’s Disease Genes and the Potentially Implicated PathwaysSemantic proximity Read ↗

LACK OF ASSOCIATIONS BETWEEN CLU AND PICALM GENE POLYMORPHISMS AND ALZHEIMER'S DISEASE IN A TURKISH POPULATION.Semantic proximity Read ↗

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