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Article

Genetic association between clusterin polymorphisms and Alzheimer's disease in a Japanese population.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society - 1 Mar 2011

Komatsu Miwa, Shibata Nobuto, Kuerban Bolati, Ohnuma Tohru, Baba Hajime, Arai Heii

Abstract excerpt

BACKGROUND: Previous papers have reported that clusterin (CLU, also called apolipoprotein J) maintains amyloid β-peptide (Aβ) solubility and protects against Aβ neurotoxicity. Recently, two large genome-wide association studies (GWAS) identified that a specific single nucleotide polymorphism (SNP) on the gene has been reported to modify the risk for Alzheimer's disease (AD). The present study aimed to investigate...

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Source

Identifiers

PMID: 21447104
DOI: 10.1111/j.1479-8301.2010.00346.x

Genes

CLU

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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