Article
The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort.
Journal of geriatric psychiatry and neurology - 1 Jul 2016
Alaylıoğlu Merve, Gezen-Ak Duygu, Dursun Erdinç, Bilgiç Başar, Hanağası Haşmet, Ertan Turan, Gürvit Hakan, Emre Murat, Eker Engin, Uysal Ömer, Yılmazer Selma
Abstract excerpt
Previous studies have demonstrated that clusterin (CLU), which is also known as apolipoprotein J, is involved in the pathogenesis of Alzheimer disease (AD). In this study, we investigated the association between rs2279590, rs11136000, and rs9331888 single-nucleotide polymorphisms (SNPs) in CLU and apolipoprotein E (APOE) genotypes in a cohort of Turkish patients with late-onset AD (LOAD). There were 183 patients...
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