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Article

TK6 genome profile compared with WIL2-NS: Reference data to improve the reproducibility of genotoxicity studies.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Jan 2000

Kasai Fumio, Hirayama Noriko, Kohara Arihiro

Abstract excerpt

The TK6 cell line has been widely used for genotoxicity screening by taking advantage of the TK1 mutations. A number of publications have employed TK6 as a tool for the assay; however, its characterization is limited. Because genomes of cell lines are often changed during cell culture, differences in TK6 genomes could be observed between laboratories, which would cause potential problems with reproducibility...

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PMID: 33198927
DOI: 10.1016/j.mrgentox.2020.503236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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