Article
Mutational spectrum of X-ray induced TK- human cell mutants.
Carcinogenesis - 1 Feb 1995
Giver C R, Nelson S L, Cha M Y, Pongsaensook P, Grosovsky A J
Abstract excerpt
Mutations induced by ionizing radiation have historically elicited significant public concern. However, only a limited database of ionizing radiation-induced point mutations is available, particularly at endogenous human cell loci. Here, we report the mutational spectrum for 184 X-ray induced TK- mutants derived from TK6 human lymphoblasts. This report represents the first large scale utilization of the tk locus...
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