Article
Mutational spectrum of X-ray induced TK- human cell mutants.
Carcinogenesis - 1 Feb 1995
Giver C R, Nelson S L, Cha M Y, Pongsaensook P, Grosovsky A J
Abstract excerpt
Mutations induced by ionizing radiation have historically elicited significant public concern. However, only a limited database of ionizing radiation-induced point mutations is available, particularly at endogenous human cell loci. Here, we report the mutational spectrum for 184 X-ray induced TK-...
Topics
- Alleles
- B-Lymphocytes
- Base Sequence
- Cell Line
- DNA Mutational Analysis
- DNA, Complementary
- Gene Deletion
- Gene Rearrangement
- Heterozygote
- Humans
- Molecular Sequence Data
- Point Mutation
- RNA Splicing
- Reproducibility of Results
- Sensitivity and Specificity
- Thymidine Kinase
- Transcription, Genetic
- X-Rays