Article
[TK locus mutation assay: comparison of L5178Y and TK6 cell lines].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Sept 2004
Shuai Pei-qiang, Zhang Li-shi, Wang Yi-jing
Abstract excerpt
OBJECTIVE: To compare the advantages and disadvantages of utilizing L5178Y and TK6 cell lines in the TK locus mutation assay. METHODS: The two cell lines were used for detecting and assessing the mutability of four chemicals (MMS, EMS, MMC and KCl); the microwell method of TK locus mutation assay was adopted. RESULTS: The two cell lines brought about similar results in the study. The tolerance of TK6 to all four...
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