Article
Comprehensive high-resolution genomic profiling and cytogenetics of human chondrocyte cultures by GTG-banding, locus-specific FISH, SKY and SNP array.
European cells & materials - 23 Apr 2018
Wallenborn M, Petters O, Rudolf D, Hantmann H, Richter M, Ahnert P, Rohani L, Smink J J, Bulwin G C, Krupp W, Schulz R M, Holland H
Abstract excerpt
In the development of cell-based medicinal products, it is crucial to guarantee that the application of such an advanced therapy medicinal product (ATMP) is safe for the patients. The consensus of the European regulatory authorities is: "In conclusion, on the basis of the state of art, conventional karyotyping can be considered a valuable and useful technique to analyse chromosomal stability during preclinical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.