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Article

[The tk gene mutation analysis in WTK1 cell line by multiplex PCR].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Sept 2006

Wang Yi-jing, Shuai Pei-qiang, Zhang Li-shi

Abstract excerpt

OBJECTIVE: To explore the tk gene mutation spectrum in spontaneous and induced WTK1 mutants. METHODS: After exposure to methyl methanesulfonate (MMS), mitomycin (MMC) or sodiam azide (NaN3), spontaneously-arising and induced mutants of WTK1 cell line were selected. The spectrum and hotspot of tk gene mutation were analyzed by multiplex PCR. RESULTS: Three chemicals used in this study induced tk mutation frequency...

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PMID: 17037754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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