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Article

Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile.

PloS one - 1 Jan 2013

Mackin Kate E, Carter Glen P, Howarth Pauline, Rood Julian I, Lyras Dena

Abstract excerpt

Clostridium difficile is an important pathogen of humans and animals, representing a significant global healthcare problem. The last decade has seen the emergence of epidemic BI/NAP1/027 and ribotype 078 isolates, associated with the onset of more severe disease and higher rates of morbidity and mortality. However, little is known about these isolates at the molecular level, partly due to difficulties in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24236153
DOI: 10.1371/journal.pone.0079666
PMCID: PMC3827441

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