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Article

Genetic variants of autophagy-related genes in the PI3K/Akt/mTOR pathway and risk of gastric cancer in the Chinese population.

Gene - 15 Feb 2021

Zheng Weiwei, Wu Chuancheng, Wu Xiaoli, Cai Yuanhuan, Liu Baoying, Wang Chengdang

Abstract excerpt

OBJECTIVE: Autophagic dysfunction could lead to tumorigenesis and affect tumor progression and prognosis. The PI3K/Akt/mTOR signaling pathway plays an important role in autophagy. The aim of the studies was to explore the association between genetic variants of autophagy-related genes in the PI3K/Akt/mTOR pathway and gastric cancer risk. METHODS: We selected candidate genes via Kyoto Encyclopedia of Genes and...

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Identifiers

PMID: 33053421
DOI: 10.1016/j.gene.2020.145190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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