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Article

A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population.

Scientific reports - 28 Jan 2016

Wang Meng-Yun, He Jing, Zhu Mei-Ling, Teng Xiao-Yan, Li Qiao-Xin, Sun Meng-Hong, Wang Xiao-Feng, Yang Ya-Jun, Wang Jiu-Cun, Jin Li, Wang Ya-Nong, Wei Qing-Yi

Abstract excerpt

AKT is an important signal transduction protein that plays a crucial role in cancer development. Therefore, we evaluated associations between single nucleotide polymorphisms (SNPs) in the AKT promoter region and gastric cancer (GCa) risk in a case-control study of 1,110 GCa patients and 1,114 matched cancer-free controls. We genotyped five SNPs (AKT1 rs2494750G >C, AKT1 rs2494752A >G, AKT1 rs10138227C >T, AKT2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26818920
DOI: 10.1038/srep20008
PMCID: PMC4730221

Genes

AKT1
AKT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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