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Article

Polymorphisms in mTORC1 genes modulate risk of esophageal squamous cell carcinoma in eastern Chinese populations.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jun 2013

Zhu Mei-Ling, Yu Hongping, Shi Ting-Yan, He Jing, Wang Meng-Yun, Li Qiao-Xin, Sun Meng-Hong, Jin Li, Yang Ya-Jun, Wang Jiu-Cun, Xiang Jia-Qing, Wei Qing-Yi

Abstract excerpt

INTRODUCTION: Mammalian target of rapamycin complex 1 (mTORC1) is an evolutionary conserved multiprotein complex that functions as a key regulator of gene transcription, protein translation, and autophagy. No studies have assessed associations between functional single nucleotide polymorphisms (SNPs) in mTORC1 genes and risk of esophageal squamous cell carcinoma (ESCC). METHODS: : In a case-control study of 1126...

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PMID: 23524405
DOI: 10.1097/JTO.0b013e31828916c6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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