Article
Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients.
International journal of cancer - 15 Jan 2019
Cheng Lei, Qiu Lixin, Zhang Ruoxin, Qian Danwen, Wang Mengyun, Sun Menghong, Zhu Xiaodong, Wang Yanong, Guo Weijian, Wei Qingyi
Abstract excerpt
We previously reported that some single nucleotide polymorphisms (SNPs) of candidate genes involved in the MTOR complex1 (MTORC1) were associated with risk of gastric cancer (GCa). In the present study, we further evaluated associations of eight potentially functional SNPs of MTOR, MLST8 and RPTOR with survival of 1002 GCa patients and also investigated molecular mechanisms underlying such associations....
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