Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.

PloS one - 1 Jan 2015

Piao Ying, Li Ying, Xu Qian, Liu Jing-wei, Xing Cheng-zhong, Xie Xiao-dong, Yuan Yuan

Abstract excerpt

BACKGROUND: The phosphoinositide 3-kinase (PI3K)/protein kinase B (PKB, AKT)/mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in angiogenesis and cell growth, proliferation, metabolism, migration, differentiation, and apoptosis. Genetic diversity in key factors of this pathway may influence protein function and signal transduction, contributing to disease initiation and progression....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gastritis, Atrophic

Share to Proto-Oncogene Proteins c-akt

Share to Stomach Neoplasms

Share to TOR Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 26317520
DOI: 10.1371/journal.pone.0136447
PMCID: PMC4552869

Genes

MTOR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.PMID 26317520Read ↗

Genetic variants in PI3K/Akt/mTOR pathway genes contribute to gastric cancer risk.Semantic proximity Read ↗

Study on the association between PI3K/AKT/mTOR signaling pathway gene polymorphism and susceptibility to gastric cancer.Semantic proximity Read ↗

Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.Semantic proximity Read ↗

Genetic variants of autophagy-related genes in the PI3K/Akt/mTOR pathway and risk of gastric cancer in the Chinese population.Semantic proximity Read ↗

Genetic variations in the mTOR gene contribute toward gastric adenocarcinoma susceptibility in an Eastern Chinese population.Semantic proximity Read ↗

Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis.Semantic proximity Read ↗

Molecular target: pan-AKT in gastric cancerSemantic proximity Read ↗

[Polymorphisms of mTORC1 genes and risk of primary colorectal adenocarcinoma in Chinese populations].Semantic proximity Read ↗

Associations of genetic polymorphisms in pTEN/AKT/mTOR signaling pathway genes with cancer risk: A meta-analysis in Asian population.Semantic proximity Read ↗

Polymorphisms in mTORC1 genes modulate risk of esophageal squamous cell carcinoma in eastern Chinese populations.Semantic proximity Read ↗

A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.Semantic proximity Read ↗

Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.