Article
Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.
PloS one - 1 Jan 2015
Piao Ying, Li Ying, Xu Qian, Liu Jing-wei, Xing Cheng-zhong, Xie Xiao-dong, Yuan Yuan
Abstract excerpt
BACKGROUND: The phosphoinositide 3-kinase (PI3K)/protein kinase B (PKB, AKT)/mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in angiogenesis and cell growth, proliferation, metabolism, migration, differentiation, and apoptosis. Genetic diversity in key factors of this...
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