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Article

Association of PI3K/AKT/mTOR pathway genetic variants with type 2 diabetes mellitus in Chinese.

Diabetes research and clinical practice - 1 Jun 2017

Yin Xueyao, Xu Zhiye, Zhang Ziyi, Li Lin, Pan Qianqian, Zheng Fenping, Li Hong

Abstract excerpt

AIMS: Genetic variations in the PI3K/AKT/mTOR signaling pathway may be associated with an increasing risk of obesity and diabetes. In this study, we aimed to test whether polymorphisms in the PIK3CA (catalytic subunit of PI3K), AKT1, AKT2, and FRAP1 (mTOR) genes were associated with the risk of type 2 diabetes mellitus (T2DM) among Chinese population. METHODS: A case-control study was conducted and included 248...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28477532
DOI: 10.1016/j.diabres.2017.04.002

Genes

AKT1
AKT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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