Article
Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.
Molecular carcinogenesis - 1 Nov 2013
He Jing, Wang Meng-Yun, Qiu Li-Xin, Zhu Mei-Ling, Shi Ting-Yan, Zhou Xiao-Yan, Sun Meng-Hong, Yang Ya-Jun, Wang Jiu-Cun, Jin Li, Wang Ya-Nong, Li Jin, Yu Hong-Ping, Wei Qing-Yi
Abstract excerpt
Mammalian target of rapamycin complex 1 (mTORC1) plays an important role in maintaining proper cellular functions, and genetic variations in this complex may affect cancer risk. In this study, we examined the associations between eight potential functional single nucleotide polymorphisms in the mTORC1 genes (rs2536T>C and rs1883965G>A for mTOR, rs3160T>C, and rs26865A>G for mLST8, rs3751934C>A, rs1062935T>C,...
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