Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Study on the association between PI3K/AKT/mTOR signaling pathway gene polymorphism and susceptibility to gastric cancer.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Qi Lei, Sun Kewen, Zhuang Yun, Yang Jing, Chen Jianping

Abstract excerpt

PURPOSE: Excessive activation of PI3K/AKT/mTOR signaling pathway is one of the most common changes in human cancers, and single nucleotide polymorphisms (SNPs) existing in its functional region can affect the occurrence process of a variety of cancers. This study aimed to screen out the SNPs associated with susceptibility to gastric cancer in the PI3K/AKT/mT0R signaling pathway. METHODS: In this case-control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Class I Phosphatidylinositol 3-Kinases

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Proto-Oncogene Proteins c-akt

Share to Signal Transduction

Share to Stomach Neoplasms

Source

Identifiers

PMID: 29332342

Genes

AKT1
AKT2
AKT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Study on the association between PI3K/AKT/mTOR signaling pathway gene polymorphism and susceptibility to gastric cancer.PMID 29332342Read ↗

Genetic variants in PI3K/Akt/mTOR pathway genes contribute to gastric cancer risk.Semantic proximity Read ↗

Genetic variants of autophagy-related genes in the PI3K/Akt/mTOR pathway and risk of gastric cancer in the Chinese population.Semantic proximity Read ↗

A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.Semantic proximity Read ↗

Associations of genetic polymorphisms in pTEN/AKT/mTOR signaling pathway genes with cancer risk: A meta-analysis in Asian population.Semantic proximity Read ↗

Association of mTOR polymorphisms with cancer risk and clinical outcomes: a meta-analysis.Semantic proximity Read ↗

Genetic variations of mTORC1 genes and risk of gastric cancer in an Eastern Chinese population.Semantic proximity Read ↗

Genetic variations in the mTOR gene contribute toward gastric adenocarcinoma susceptibility in an Eastern Chinese population.Semantic proximity Read ↗

Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.Semantic proximity Read ↗

Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis.Semantic proximity Read ↗

Impacts of the mTOR gene polymorphisms rs2536 and rs2295080 on breast cancer risk in the Chinese population.Semantic proximity Read ↗

[Polymorphisms of mTORC1 genes and risk of primary colorectal adenocarcinoma in Chinese populations].Semantic proximity Read ↗

Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.