A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.

doi:10.1371/journal.pone.0060080

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Article

A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.

PloS one - 1 Jan 2013

Xu Ming, Tao Guoquan, Kang Meiyun, Gao Yan, Zhu Haixia, Gong Weida, Wang Meilin, Wu Dongmei, Zhang Zhengdong, Zhao Qinghong

Abstract excerpt

BACKGROUND: As an imperative part of PI3K/Akt/mTOR pathway, mammalian target of rapamycin (mTOR) has been demonstrated to increase in gastric cancer cells and tumors. Our research explored the relationship between single nucleotide polymorphism (SNP) rs2295080 in mTOR promoter region and the risk of gastric cancer (GC). METHODS: Seven hundred and fifty-three (753) gastric adenocarcinoma patients and 854 matched...

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PMID: 23555892
DOI: 10.1371/journal.pone.0060080
PMCID: PMC3612103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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