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Article

Genetic variants of TAS2R38 bitter taste receptor associate with distinct gut microbiota traits in Parkinson's disease: A pilot study.

International journal of biological macromolecules - 15 Dec 2020

Vascellari Sarah, Melis Melania, Cossu Giovanni, Melis Marta, Serra Alessandra, Palmas Vanessa, Perra Daniela, Oppo Valentina, Fiorini Michele, Cusano Roberto, Morelli Micaela, Manzin Aldo, Barbarossa Iole Tomassini

Abstract excerpt

The non-tasting form of the bitter taste receptor, TAS2R38, has been shown as a genetic risk factor associated with the development of Parkinson's disease (PD). Specific taste receptors that are expressed in the lower gastrointestinal tract may respond to alteration in gut microbiota composition,...

Topics

Aged
Clostridium
Female
Gastrointestinal Microbiome
Genetic Variation
Humans
Male
Middle Aged
Parkinson Disease
Pilot Projects
Receptors, G-Protein-Coupled

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Taste Receptors, Type 2

Source

Identifiers

PMID: 32946938
DOI: 10.1016/j.ijbiomac.2020.09.056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-32946938-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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