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Article

Distribution of TAS2R38 bitter taste receptor phenotype and haplotypes among COVID-19 patients.

Scientific reports - 5 May 2022

Risso D, Carmagnola D, Morini G, Pellegrini G, Canciani E, Antinucci M, Henin D, Dellavia C

Abstract excerpt

Bitter taste receptor TAS2R38 is expressed in the respiratory tract and can respond to quorum-sensing molecules produced by pathogens, stimulating the release of nitric oxide, with biocidal activity. TAS2R38 presents two main high-frequency haplotypes: the "taster" PAV and the "non-taster" AVI. Individuals carrying the AVI allele could be at greater risk of infections, including SARS-CoV-2. The aim of this study...

Topics

COVID-19
Genotype
Haplotypes
Humans
Phenotype
Polymorphism, Single Nucleotide
Receptors, G-Protein-Coupled
SARS-CoV-2
Taste
Taste Perception

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35513681
DOI: 10.1038/s41598-022-10747-2
PMCID: PMC9070615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-35513681-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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