Article
6-n-propylthiouracil taste disruption and TAS2R38 nontasting form in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2018
Cossu Giovanni, Melis Melania, Sarchioto Marianna, Melis Marta, Melis Maurizio, Morelli Micaela, Tomassini Barbarossa Iole
Abstract excerpt
BACKGROUND: The few studies that evaluated taste function in Parkinson's disease (PD) showed inconsistent results. The inherited ability to taste the bitter compound of 6-n-propylthiouracil has been considered to be a paradigm of general taste perception. 6-n-propylthiouracil taste perception is...
Topics
- Aged
- Antimetabolites
- Case-Control Studies
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Parkinson Disease
- Polymorphism, Single Nucleotide
- Propylthiouracil
- Receptors, G-Protein-Coupled
- Severity of Illness Index
- Statistics, Nonparametric
- Taste
- Taste Disorders
- Taste Perception
- Taste Receptors, Type 2