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Article

6-n-propylthiouracil taste disruption and TAS2R38 nontasting form in Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2018

Cossu Giovanni, Melis Melania, Sarchioto Marianna, Melis Marta, Melis Maurizio, Morelli Micaela, Tomassini Barbarossa Iole

Abstract excerpt

BACKGROUND: The few studies that evaluated taste function in Parkinson's disease (PD) showed inconsistent results. The inherited ability to taste the bitter compound of 6-n-propylthiouracil has been considered to be a paradigm of general taste perception. 6-n-propylthiouracil taste perception is mediated by the TAS2R38 receptor, and reduced 6-n-propylthiouracil sensitivity has been associated with several...

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PMID: 29575306
DOI: 10.1002/mds.27391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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