Article
Genetic, functional, and phenotypic diversity in TAS2R38-mediated bitter taste perception.
Chemical senses - 1 Jul 2013
Behrens Maik, Gunn Howard C, Ramos Purita C M, Meyerhof Wolfgang, Wooding Stephen P
Abstract excerpt
Mutational polymorphism in the TAS2R38 bitter taste receptor is a key determinant of threshold taste detection of isolated compounds, such as phenylthiocarbamide (PTC) and propylthiouracil (PROP), as well as complex orosensation-mediated traits such as diet choice and smoking habits. These relationships are accounted for, in part, by 2 common alleles differing in functionality, TAS2R38-PAV and TAS2R38-AVI....
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