Genetic, functional, and phenotypic diversity in TAS2R38-mediated bitter taste perception.

doi:10.1093/chemse/bjt016

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Article

Genetic, functional, and phenotypic diversity in TAS2R38-mediated bitter taste perception.

Chemical senses - 1 Jul 2013

Behrens Maik, Gunn Howard C, Ramos Purita C M, Meyerhof Wolfgang, Wooding Stephen P

Abstract excerpt

Mutational polymorphism in the TAS2R38 bitter taste receptor is a key determinant of threshold taste detection of isolated compounds, such as phenylthiocarbamide (PTC) and propylthiouracil (PROP), as well as complex orosensation-mediated traits such as diet choice and smoking habits. These relati...

Topics

Adult
Alleles
Female
Genetic Variation
Humans
Male
Phenotype
Polymorphism, Single Nucleotide
Receptors, G-Protein-Coupled
Taste Perception
Taste Receptors, Type 2

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