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Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury.

Cellular & molecular immunology - 1 May 2021

Sakai Ryota, Ito Minako, Komai Kyoko, Iizuka-Koga Mana, Matsuo Kazuhiko, Nakayama Takashi, Yoshie Osamu, Amano Koichi, Nishimasu Hiroshi, Nureki Osamu, Kubo Masato, Yoshimura Akihiko

Abstract excerpt

FoxP3+ regulatory T cells (Tregs) play crucial roles in peripheral immune tolerance. In addition, Tregs that reside or accumulate in nonlymphoid tissues, called tissue Tregs, exhibit tissue-specific functions and contribute to the maintenance of tissue homeostasis and repair. In an experimental mouse model of crescentic glomerulonephritis induced by an anti-glomerular basement membrane antibody, Tregs started to...

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Identifiers

PMID: 32917984
DOI: 10.1038/s41423-020-00547-x
PMCID: PMC8093306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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