Article
Regulatory T cells in immune-mediated renal disease.
Nephrology (Carlton, Vic.) - 1 Feb 2016
Ghali Joanna R, Wang Yuan Min, Holdsworth Stephen R, Kitching A Richard
Abstract excerpt
Regulatory T cells (Tregs) are CD4+ T cells that can suppress immune responses by effector T cells, B cells and innate immune cells. This review discusses the role that Tregs play in murine models of immune-mediated renal diseases and acute kidney injury and in human autoimmune kidney disease (such as systemic lupus erythematosus, anti-glomerular basement membrane disease, anti-neutrophil cytoplasmic...
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