Article

Immunomodulatory Functions of Intercalated Cells in Kidney Autoimmunity

2025-11-16

Abstract excerpt

Various autoimmune diseases frequently cause both acute and chronic kidney injuries through complex mechanisms involving autoantibodies and cellular immune responses that result in tissue damage. Intercalated cells (ICs), specialized renal tubular epithelial cells responsible for proton secretion, are strategically positioned at the epithelial-immune interface, making them ideal sensors of stress signals and poten...

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Literature Corpus work: f5bcc329-ece4-5cb1-b5b2-5e1c0a54a1b0
DOI: 10.1101/2025.11.14.688275

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