Article
Regulatory T cells in acute and chronic kidney diseases.
American journal of physiology. Renal physiology - 1 May 2018
Sharma Rahul, Kinsey Gilbert R
Abstract excerpt
Foxp3-expressing CD4+ regulatory T cells (Tregs) make up one subset of the helper T cells (Th) and are one of the major mechanisms of peripheral tolerance. Tregs prevent abnormal activation of the immune system throughout the lifespan, thus protecting from autoimmune and inflammatory diseases. Recent studies have elucidated the role of Tregs beyond autoimmunity. Tregs play important functions in controlling not...
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