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Article

Characterization of the renal CD4+ T-cell response in experimental autoimmune glomerulonephritis.

Kidney international - 1 Jul 2012

Hopfer Helmut, Holzer Julia, Hünemörder Stefanie, Paust Hans-Joachim, Sachs Marlies, Meyer-Schwesinger Catherine, Turner Jan-Eric, Panzer Ulf, Mittrücker Hans-Willi

Abstract excerpt

Autoimmunity against the Goodpasture antigen α3IV-NC1 results in antiglomerular basement membrane glomerulonephritis. Although antibodies are central to the pathogenesis, there is good evidence for the participation of T cells in this disease. To define the contribution of T cells, we used the model of experimental autoimmune glomerulonephritis. Immunization of DBA/1 mice with α3IV-NC1 resulted in proteinuria, a...

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PMID: 22437418
DOI: 10.1038/ki.2012.73

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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