Article
An altered glial phenotype in the NL3R451C mouse model of autism.
Scientific reports - 2 Sept 2020
Matta Samantha M, Moore Zachery, Walker Frederick Rohan, Hill-Yardin Elisa L, Crack Peter J
Abstract excerpt
Autism Spectrum Disorder (ASD; autism) is a neurodevelopmental disorder characterised by deficits in social communication, and restricted and/or repetitive behaviours. While the precise pathophysiologies are unclear, increasing evidence supports a role for dysregulated neuroinflammation in the brain with potential effects on synapse function. Here, we studied characteristics of microglia and astrocytes in the...
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