Article
A review on the current neuroligin mouse models.
Sheng li xue bao : [Acta physiologica Sinica] - 25 Oct 2012
Xu Jun-Yu, Xia Qiang-Qiang, Xia Jun
Abstract excerpt
Neuroligins (NLs) are postsynaptic membrane proteins expressed in the brain and mediate synaptogenesis. Neuroligin family proteins can specifically induce either excitatory or inhibitory synapses. Deletions or point mutations in neuroligin genes are found in patients with autism spectrum disorders (ASD) or mental retardations. The dysfunctions of these mutations have been tested in multiple neuroligin mouse...
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